Two simple, precise and cost effective spectrophotometric methods have been developed for the estimation of Valsartan in bulk and its pharmaceutical formulations. Valsartan shows λmax at 250 nm in zero order derivative spectrum (Method A) and 265 nm in first order derivative spectrum (Method B). The drug follows the Beer-Lambert’s law in the concentration range of 10–55 µg/ml in both the methods. The methods were validated by following the analytical performance parameters as suggested by the International Conference on Harmonization which included accuracy, precision, interday and intraday assay, robustness, and ruggedness. All validation parameters were within the acceptable range. The developed methods were successfully applied to estimate the amount of Valsartan in bulk and pharmaceutical dosage forms. This method can be used for the routine estimation of Valsartan in industries and other analytical laboratories and also in dissolution studies.
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